SSTR2 anticorps (Extracellular, N-Term)

N° du produit ABIN7885527

Cet anticorps Lapin Polyclonal détecte spécifiquement SSTR2 dans WB, IHC, FACS, IF, LCI et IC. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour SSTR2 anticorps (Extracellular, N-Term) (ABIN7885527)

Antigène: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SSTR2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Live Cell Imaging (LCI), Immunochromatography (IC)

Classe de qualité: Carrier-free

Détail du produit anti-SSTR2 anticorps

Épitope: AA 30-43, Extracellular, N-Term

Fonction: A Rabbit Polyclonal Antibody to Somatostatin Receptor Type 2

Homologie: Mouse - identical, human- 12,14 amino acid residues identical

Purification: Affinity purified on immobilized antigen.

Immunogène: (C)GSNQTEPYYDMTSN, corresponding to amino acid residues 30-43 of rat SSTR2

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:200

FC: 5 mg per reaction

ICC: 1:50

IHC: 1:100

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: BLP-SR006

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW)

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur SSTR2

Antigène: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Autre désignation: SSTR2

Sujet:

Synonyms: SSTR2, SS2R, Smstr2, SRIF1A

Description: Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues.1 In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain, it acts as a neurotransmitter in both a stimulatory and an inhibitory manner.1,2Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4, and SSTR5), which are encoded by five genes.1,2 Expression of the different receptors is developmentally regulated in a time- and tissue-specific manner.2Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids, and breast tumors.3 Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in vivo imaging of tumors that are positive for somatostatin receptors.4In general, SSTR2 is the most common SSTR subtype found in human tumors, followed by SSTR1, with SSTR3 and SSTR4 being less common.

ID gène: 54305

UniProt: P30680