UTS2R anticorps (2nd Cytoplasmic Loop)

N° du produit ABIN7885632

Cet anticorps Lapin Polyclonal détecte spécifiquement UTS2R dans WB et IHC. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour UTS2R anticorps (2nd Cytoplasmic Loop) (ABIN7885632)

Antigène: UTS2R (Urotensin 2 Receptor (UTS2R))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UTS2R est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Classe de qualité: Carrier-free

Détail du produit anti-UTS2R anticorps

Épitope: 2nd Cytoplasmic Loop, AA 154-167

Fonction: A Rabbit Ployclonal Antibody to Urotensin II Receptor

Homologie: Bovine - identical, human,canine - 13,14 amino acid residues identical

Purification: Affinity purified on immobilized antigen.

Immunogène: (C)RPLDTVQRSKGYRK, corresponding to amino acid residues 154-167 of rat URIIR

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: (ABIN7237551)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW)

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur UTS2R

Antigène: UTS2R (Urotensin 2 Receptor (UTS2R))

Autre désignation: Urotensin 2 receptor

Sujet:

Synonyms: Urotensin 2 receptor, UR-II-R, UR2R, UTS2R, SENR, GPR14

Description: Urotensin II is a powerful vasoconstrictive substance. The human urotensin II receptor (UR-II-R) was originally isolated as an orphan receptor (GPR14) from neural and sensory tissues.1,2 Urotensin II is expressed in various human tissues such as the CNS, skeletal muscle, smooth muscle, pancreas, and heart.3-5 Binding of urotensin II to the receptor leads to activation of phospholipase C. The resulting increase in intracellular Ca2+ may cause the contraction of vascular smooth muscle. ERK1/2 phophorylation may also be involved in mediating the biological activities of urotensin II.6 Recently, evidence has accumulated indicating that urotensin II is also expressed in various kinds of tumor cells such as adrenal tumors and neuroblastomas. In those cells, urotensin II was reported to stimulate cell growth.7-9

ID gène: 57305

UniProt: P49684