NCOA3 anticorps (pThr24)

N° du produit ABIN745883

L’anticorps Lapin Polyclonal anti-NCOA3 a été validé pour ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Il convient pour détecter NCOA3 dans des échantillons de Humain.

Aperçu rapide pour NCOA3 anticorps (pThr24) (ABIN745883)

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOA3 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-NCOA3 anticorps

Épitope: pThr24

Réactivité croisée: Humain

Homologie: Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human SRC-3 around the phosphorylation site of Thr24

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur NCOA3

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Autre désignation: Src-3

Sujet:

Synonyms: ACTR, AIB 1, AIB-1, AIB1, Amplied in breast cancer 1, Amplied in breast cancer 1 protein, bHLHe42, CAGH 16, CAGH16, CBP interacting protein, CBP-interacting protein, Class E basic helix-loop-helix protein 42, CTG 26, CTG26, KAT13B / AIB1, MGC141848, NCOA 3, NCOA 3, NCoA-3, Ncoa3, NCOA3_HUMAN, Nuclear receptor coactivator 3, pCIP, RAC 3, RAC-3, RAC3, Receptor associated coactivator 3, Receptor-associated coactivator 3, SRC 3, SRC-3, SRC3, Steroid receptor coactivator protein 3, Thyroid hormone receptor activator molecule 1, TNRC14, TNRC16, TRAM 1, TRAM-1, TRAM1.

Background: KAT13B/AIB1 interacts in a ligand-dependent fashion with the estrogen receptor to enhance estrogen-dependent transcriptional gene activation. The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits KAT3A / KAT3B as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.

ID gène: 8202

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha