SYK anticorps (pTyr323) (Cy5)

N° du produit ABIN746262

Cet anticorps anti-SYK est un anticorps Lapin Polyclonal détectant SYK dans WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SYK anticorps (pTyr323) (Cy5) (ABIN746262)

Antigène: SYK (Spleen tyrosine Kinase (SYK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYK est conjugé à/à la Cy5

Application: Western Blotting (WB)

Détail du produit anti-SYK anticorps (Cy5)

Épitope: pTyr323

Réactivité croisée: Souris

Homologie: Human,Rat,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Syk around the phosphorylation site of Tyr323

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SYK

Antigène: SYK (Spleen tyrosine Kinase (SYK))

Autre désignation: Syk

Sujet:

Synonyms: syk Tyr323, Tyrosine-protein kinase SYK Spleen tyrosine kinase [Contains: 72 kDa tyrosine-protein kinase SYK, 40 kDa tyrosine-protein kinase SYK, KSYK_HUMAN.

Background: Syk (72 kDa) is a non receptor protein tyrosine kinase that plays an important role in immune receptor signal transduction and is implicated in endothelial cell functions, including cell growth and migration. SYK is a positive effector of BCR stimulated responses. It couples the B cell antigen receptor (BCR) to the mobilization of calcium ions either through a phosphoinositide 3 kinase dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C gamma dependent pathway, when phosphorylated on Tyr 342 and Tyr 346. Thus the differential phosphorylation of SYK can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ions. Alternate Names: p72syk, Spleen tyrosine kinase, Tyrosine protein kinase SYK.

ID gène: 6850

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling