Recombinant BCL6 anticorps

N° du produit ABIN7938057

Cet anticorps anti-BCL6 Monoclonal Lapin (Clone 3K6) (ABIN7938057) détecte spécifiquement BCL6 dans WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant BCL6 anticorps (ABIN7938057)

Antigène: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL6 est non-conjugé

Application: Western Blotting (WB)

Clone: 3K6

Détail du produit anti-BCL6 anticorps

Fonction: BCL6 antibody (rAb), 100 μg (Clone 3K6)

Purification: Protein A Chromatography

Immunogène: This antibody was raised against the BCL6 fusion protein.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:5000-1:50000 dilution

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur BCL6

Antigène: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Autre désignation: BCL6

Sujet:

Background_Plain: BCL6, a zinc finger transcription factor, contains an N-terminal BTB/POZ domain and C-terminal zinc finger DNA-binding motifs and represses transcription of a wide range of target proteins and microRNAs. BCL6 protein has been reported as a master regulator of B lymphocyte development and growth and altered BCL6 protein expression was implicated in pathogenesis of diverse human hematologic malignancies, especially in the diffuse large B cell lymphoma (DLBCL). BCL6 is required for the development of T follicular helper T cells (TFH), a helper T cell subset required for the formation of mature and productive GCs. BCL6 has also been shown to play important regulatory roles in macrophages.

Aliases: B-Cell CLL/Lymphoma 6, BCL5, LAZ3, BCL6A, ZNF51, ZBTB27

Poids moléculaire: 79 kDa

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus