DPPA4 anticorps

N° du produit ABIN7938109

Cet anticorps Lapin Polyclonal détecte spécifiquement DPPA4 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour DPPA4 anticorps (ABIN7938109)

Antigène: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPPA4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DPPA4 anticorps

Fonction: DPPA4 antibody (pAb)

Purification: Protein A Chromatography

Immunogène: This antibody was raised against a peptide corresponding to DPPA4.

Isotype: IgG

Information d'application

Indications d'application: WB: 0.5 μg/mL-2 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur DPPA4

Antigène: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Autre désignation: DPPA4

Sujet:

Background_Plain: DPPA2 and DPPA4 (developmental pluripotency associated 2 and 4) are small heterodimerizing nuclear proteins linked in the biological processes of transcription and transcription regulation. The encoded proteins have a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. The nuclear factor encoded by the gene is involved in the maintenance of pluripotency in stem cells and is found to be essential for embryogenesis. DPPA2 and DPPA4 are required to maintain H3K4me3 and H3K27me3 at important bivalent promoters depicted in pluripotent cells by low H3K4me3 levels and initiating but not elongating RNA polymerase II. This gene is thought to play an important role in tumor progression because when mutated it is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers.

Aliases: Developmental Pluripotency Associated 4

Poids moléculaire: 42 kDa

NCBI Accession: NP_001335858