Recombinant CBX5 anticorps

N° du produit ABIN7938268

Cet anticorps Lapin Monoclonal détecte spécifiquement CBX5 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant CBX5 anticorps (ABIN7938268)

Antigène: CBX5 (Chromobox Homolog 5 (CBX5))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CBX5 est non-conjugé

Application: Western Blotting (WB)

Clone: 240145F11

Détail du produit anti-CBX5 anticorps

Fonction: HP1 antibody (rAb), 100 μg (Clone 240145F11)

Purification: Protein A Chromatography

Immunogène: This antibody was raised against the HP1 fusion protein.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:5000-1:50000 dilution

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur CBX5

Antigène: CBX5 (Chromobox Homolog 5 (CBX5))

Autre désignation: HP1

Sujet:

Background_Plain: HP1 (Heterochromatin protein 1) is a chromosomal protein that participates in both chromatin packaging and gene silencing. Three HP1 isoforms (a, b and g) occur in mammals. The chromodomain (Chromatin Organization Modifier) of HP1a is responsible for binding to Histone H3 methyl Lys9, although additional factors are required to specify the HP1 targeting. The chromoshadow domain mediates interactions with a number of nuclear proteins, including SuvH39 (a Histone H3 Lysine methyltransferase), the DNA methyltransferases DNMT1 and DNMT3A or the large subunit of the chromatin assembly factor-1 (CAF-1). Dysfunction of HP1a plays a critical role in tumorigenesis, and is implicated in the invasive/metastatic phenotype of breast cancer.

Aliases: CBX5, HP1, Hp1a

Poids moléculaire: 22 kDa