METTL16 anticorps

N° du produit ABIN7938346

L’anticorps anti-METTL16 Polyclonal Lapin est utilisé pour la détection de METTL16 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour METTL16 anticorps (ABIN7938346)

Antigène: METTL16 (Methyltransferase Like 16 (METTL16))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp METTL16 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-METTL16 anticorps

Fonction: METTL16 antibody (pAb)

Purification: Protein A Chromatography

Immunogène: This METTL16 antibody was raised against a fusion protein corresponding to human METTL16.

Isotype: IgG

Information d'application

Indications d'application: WB: 0.5 μg/mL-2 μg/mL For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.05 % Tween 20 to all blocking solutions may also reduce background. Individual optimization may be required.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur METTL16

Antigène: METTL16 (Methyltransferase Like 16 (METTL16))

Autre désignation: METTL16

Sujet:

Background_Plain: N6-methylated adenine (m6A) is prevalently present in nearly all RNA types and can be found in all organisms from bacteria to humans. It preferentially appears around stop codons and within long internal exons in mammalian messager RNAs. m6A plays an important role in the efficiency of mRNA splicing, processing, translation efficiency, editing and mRNA stability. m6A also occurs in other RNA molecules, such as primary miRNA (pri-miRNAs). METTL16 (Methyltransferase-Like Protein 16) is an RNA N6-methyltransferase that methylates adenosine residues of a subset of mRNAs and U6 smaller nuclear RNAs. METTL16 controls a significant portion of m6A epitranscriptome by regulating SAM homeostasis and plays a role in S-adenosyl-L-methionine homeostasis by regulating the expression of MAT2A transcripts.

Aliases: Methyltransferase-Like Protein 16

Poids moléculaire: 64.9 kDa

NCBI Accession: NP_076991