TRIM37 anticorps (C-Term)

N° du produit ABIN7938530

L’anticorps anti-TRIM37 Polyclonal Lapin est utilisé pour la détection de TRIM37 dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour TRIM37 anticorps (C-Term) (ABIN7938530)

Antigène: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM37 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRIM37 anticorps

Épitope: C-Term

Fonction: TRIM37 antibody (pAb), sample

Purification: Affinity Purified

Immunogène: This antibody was raised against a peptide within the C-terminal region of human TRIM37.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2,000 dilution

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur TRIM37

Antigène: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Autre désignation: TRIM37

Sujet:

Background_Plain: TRIM37 (Tripartite Motif Containing 37) is an E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972). Mediates monoubiquitination of Lys-119 of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042). Has anti-HIV activity (PubMed:24317724).

Aliases: MUL, POB1, TEF3

Poids moléculaire: 120 kDa

NCBI Accession: NP_056109