ACP2 anticorps (AA 31-88) (Fluoro647)

N° du produit ABIN7965548

L’anticorps anti-ACP2 Polyclonal Lapin est utilisé pour la détection de ACP2 dans des échantillons de Humain, Rat et Souris. Il a été validé pour FACS.

Aperçu rapide pour ACP2 anticorps (AA 31-88) (Fluoro647) (ABIN7965548)

Antigène: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACP2 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-ACP2 anticorps (Fluoro647)

Épitope: AA 31-88

Fonction: Anti-ACP2 Antibody Fluoro647 Conjugated

Homologie: Human ACP2 shares 98.3%,96.6% amino acid (aa) sequence identity with mouse,rat ACP2,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ACP2 recombinant protein (Position: R31-H88). Human ACP2 shares 98.3% and 96.6% amino acid (aa) sequence identity with mouse and rat ACP2, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ACP2

Antigène: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Autre désignation: ACP2

Sujet:

Background: Lysosomal acid phosphatase is an enzyme that in humans is encoded by the ACP2 gene. The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism.

Gene Full Name: acid phosphatase 2, lysosomal

ID gène: 53

UniProt: P11117