APRT anticorps (N-Term) (Fluoro647)

N° du produit ABIN7966593

Cet anticorps anti-APRT Polyclonal Lapin conjugué à Fluoro647 (ABIN7966593) détecte spécifiquement APRT dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour APRT anticorps (N-Term) (Fluoro647) (ABIN7966593)

Antigène: APRT (Adenine Phosphoribosyltransferase (APRT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APRT est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-APRT anticorps (Fluoro647)

Épitope: N-Term

Fonction: Anti-APRT Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by ten amino acids,and from the related rat sequence by nine amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human APRT, different from the related mouse sequence by ten amino acids, and from the related rat sequence by nine amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur APRT

Antigène: APRT (Adenine Phosphoribosyltransferase (APRT))

Autre désignation: APRT

Sujet:

Background: Adenine phosphoribosyltransferase (APRTase) is an enzyme encoded by the APRT gene, found in humans on chromosome 16. It belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: adenine phosphoribosyltransferase

ID gène: 353

UniProt: P07741

Pathways: Ribonucleoside Biosynthetic Process