AGRN anticorps (AA 1864-2068) (HRP)

N° du produit ABIN7967228

L’anticorps anti-AGRN Polyclonal Lapin est utilisé pour la détection de AGRN dans des échantillons de Humain, Rat et Souris. Il a été validé pour IHC, WB et ELISA.

Aperçu rapide pour AGRN anticorps (AA 1864-2068) (HRP) (ABIN7967228)

Antigène: AGRN (Agrin (AGRN))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGRN est conjugé à/à la HRP

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Détail du produit anti-AGRN anticorps (HRP)

Épitope: AA 1864-2068

Fonction: Anti-Agrin/AGRN Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Agrin/AGRN recombinant protein (Position: S1864-P2068).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur AGRN

Antigène: AGRN (Agrin (AGRN))

Autre désignation: AGRN

Sujet:

Background: Agrin is a protein that in humans is encoded by the AGRN gene. It is mapped to 1p36.33. This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: agrin

ID gène: 375790

UniProt: O00468

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development