alpha Fetoprotein anticorps (AA 378-609) (Fluoro488)

N° du produit ABIN7967917

Cet anticorps Lapin Polyclonal détecte spécifiquement alpha Fetoprotein dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour alpha Fetoprotein anticorps (AA 378-609) (Fluoro488) (ABIN7967917)

Antigène: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Fetoprotein est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-alpha Fetoprotein anticorps (Fluoro488)

Épitope: AA 378-609

Fonction: Anti-alpha 1 Fetoprotein/AFP Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human AFP shares 71%,73% amino acid (aa) sequences identity with mouse,rat AFP,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human AFP recombinant protein (Position: Q378-V609). Human AFP shares 71% and 73% amino acid (aa) sequences identity with mouse and rat AFP, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur alpha Fetoprotein

Antigène: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Autre désignation: AFP

Sujet:

Background: AFP, also called Alpha-fetoprotein, alpha-fetoprotein, is a protein that in humans is encoded by the AFP gene. It is mapped to 4q13.3. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. In rodents AFP binds estradiol to prevent the transport of this hormone across the placenta to the fetus. The main function of this is to prevent the virilization of female fetuses. Moreover, it has an important role as a diagnostic marker, especially in certain tumors and liver diseases of childhood. AFP is also used to test the potential usefulness of plasma alpha fetoprotein determination as a diagnostic marker in biliary atresia, hepatitis, and yolk sac derived tumours.

Gene Full Name: alpha fetoprotein

Sequence Similarities: Belongs to the ALB/AFP/VDB family.

ID gène: 174

UniProt: P02771

Pathways: C21-Steroid Hormone Metabolic Process