alpha Fetoprotein anticorps (AA 378-609)
Aperçu rapide pour alpha Fetoprotein anticorps (AA 378-609) (ABIN7967925)
Antigène
Voir toutes alpha Fetoprotein (AFP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 378-609
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Fonction
- Anti-alpha 1 Fetoprotein/AFP Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- Human AFP shares 71%,73% amino acid (aa) sequences identity with mouse,rat AFP,respectively.
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Attributs du produit
- Anti-alpha 1 Fetoprotein/AFP Antibody. Tested in IHC, WB applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human AFP recombinant protein (Position: Q378-V609). Human AFP shares 71% and 73% amino acid (aa) sequences identity with mouse and rat AFP, respectively.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
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Autre désignation
- AFP
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Sujet
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Background: AFP, also called Alpha-fetoprotein, alpha-fetoprotein, is a protein that in humans is encoded by the AFP gene. It is mapped to 4q13.3. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. In rodents AFP binds estradiol to prevent the transport of this hormone across the placenta to the fetus. The main function of this is to prevent the virilization of female fetuses. Moreover, it has an important role as a diagnostic marker, especially in certain tumors and liver diseases of childhood. AFP is also used to test the potential usefulness of plasma alpha fetoprotein determination as a diagnostic marker in biliary atresia, hepatitis, and yolk sac derived tumours.
Gene Full Name: alpha fetoprotein
Sequence Similarities: Belongs to the ALB/AFP/VDB family.
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Poids moléculaire
- 69 kDa
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ID gène
- 174
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UniProt
- P02771
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Pathways
- C21-Steroid Hormone Metabolic Process
Antigène
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