ASIC3 anticorps (N-Term)

N° du produit ABIN7968046

Cet anticorps Lapin Polyclonal détecte spécifiquement ASIC3 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour ASIC3 anticorps (N-Term) (ABIN7968046)

Antigène: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASIC3 est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: Carrier-free

Détail du produit anti-ASIC3 anticorps

Épitope: N-Term

Fonction: Anti-Acid-sensing ion channel 3 ASIC3 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related rat,mouse sequences by two amino acids.

Attributs du produit: Anti-Acid-sensing ion channel 3 ASIC3 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human ASIC3, different from the related rat and mouse sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ASIC3

Antigène: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Autre désignation: ASIC3

Sujet:

Background: ASIC3 (Acid-Sensing Ion Channel3), also known as TESTIS SODIUM CHANNEL 1 (TNAC1) or DORSAL ROOT ACID-SENSING ION CHANNEL (DRASIC), is a protein that in humans is encoded by the ASIC3 gene. ASIC3 belongs to a family of acid-sensing channel proteins that are structurally related to epithelial sodium channel proteins and support acid-activated membrane currents. By radiation hybrid analysis, de Weille et al. (1998) mapped the ACCN3 gene to chromosome 7q35. De Weille et al. (1998) found that human ASIC3 supported an H (+)-gated cation current in COS cells with kinetics similar to those of rat Asic3. Babinski et al. (1999) expressed homomeric human ASIC3 channels in Xenopus oocytes and found that rapid reduction in extracellular pH resulted in a biphasic response characterized by a fast and rapidly desensitizing current followed by a slow and sustained current that returned to baseline only on return to physiologic pH .

Gene Full Name: acid sensing ion channel subunit 3

Sequence Similarities: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC3 subfamily.

Poids moléculaire: 59 kDa

ID gène: 9311

UniProt: Q9UHC3