Aminoacylase 1 anticorps (AA 8-354) (Fluoro647)

N° du produit ABIN7968078

Cet anticorps anti-Aminoacylase 1 Polyclonal Lapin conjugué à Fluoro647 (ABIN7968078) détecte spécifiquement Aminoacylase 1 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Aminoacylase 1 anticorps (AA 8-354) (Fluoro647) (ABIN7968078)

Antigène: Aminoacylase 1 (ACY1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aminoacylase 1 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-Aminoacylase 1 anticorps (Fluoro647)

Épitope: AA 8-354

Fonction: Anti-ACY-1/ACY1 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ACY-1/ACY1 recombinant protein (Position: E8-A354).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Aminoacylase 1

Antigène: Aminoacylase 1 (ACY1)

Autre désignation: ACY1

Sujet:

Background: Aminoacylase-1 is an enzyme that in humans is encoded by the ACY1 gene. This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.

Gene Full Name: aminoacylase 1

ID gène: 95

UniProt: Q03154