ALAS1 anticorps (AA 1-244) (APC)

N° du produit ABIN7968098

L’anticorps anti-ALAS1 Polyclonal Lapin est utilisé pour la détection de ALAS1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour ALAS1 anticorps (AA 1-244) (APC) (ABIN7968098)

Antigène: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALAS1 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-ALAS1 anticorps (APC)

Épitope: AA 1-244

Fonction: Anti-Alas1 Antibody APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Alas1 recombinant protein (Position: M1-Q244).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ALAS1

Antigène: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Autre désignation: ALAS1

Sujet:

Background: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: 5'-aminolevulinate synthase 1

ID gène: 211

UniProt: P13196

Pathways: Regulation of Lipid Metabolism by PPARalpha