ANAPC5 anticorps (AA 1-266) (Fluoro488)

N° du produit ABIN7968368

L’anticorps anti-ANAPC5 Polyclonal Lapin est utilisé pour la détection de ANAPC5 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour ANAPC5 anticorps (AA 1-266) (Fluoro488) (ABIN7968368)

Antigène: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANAPC5 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-ANAPC5 anticorps (Fluoro488)

Épitope: AA 1-266

Fonction: Anti-Apc5/ANAPC5 Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Apc5/ANAPC5 recombinant protein (Position: M1-D266).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ANAPC5

Antigène: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Autre désignation: ANAPC5

Sujet:

Background: Anaphase-promoting complex subunit 5 is an enzyme that in humans is encoded by the ANAPC5 gene. This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

Gene Full Name: anaphase promoting complex subunit 5

ID gène: 51433

UniProt: Q9UJX4

Pathways: M Phase