ANGPTL4 anticorps (AA 39-406) (PE)

N° du produit ABIN7968605

L’anticorps anti-ANGPTL4 Polyclonal Lapin est utilisé pour la détection de ANGPTL4 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour ANGPTL4 anticorps (AA 39-406) (PE) (ABIN7968605)

Antigène: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANGPTL4 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-ANGPTL4 anticorps (PE)

Épitope: AA 39-406

Fonction: Anti-ANGPTL4 Antibody PE Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human ANGPTL4 shares 75.6%,76.6% amino acid (aa) sequence identity with mouse,rat ANGPTL4,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ANGPTL4 recombinant protein (Position: D39-S406). Human ANGPTL4 shares 75.6% and 76.6% amino acid (aa) sequence identity with mouse and rat ANGPTL4, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ANGPTL4

Antigène: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Autre désignation: ANGPTL4

Sujet:

Background: Angiopoietin-like 4 is a protein that in humans is encoded by the ANGPTL4 gene.[5][6][7] Alternatively spliced transcript variants encoded with different isoforms have been described. This gene was previously referred to as ANGPTL2, HFARP, PGAR, or FIAF but has been renamed ANGPTL4. This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.

Gene Full Name: angiopoietin like 4

ID gène: 51129

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha