ANGPTL4 anticorps (AA 39-406)

N° du produit ABIN7968607

Cet anticorps Lapin Polyclonal détecte spécifiquement ANGPTL4 dans WB, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour ANGPTL4 anticorps (AA 39-406) (ABIN7968607)

Antigène: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANGPTL4 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Détail du produit anti-ANGPTL4 anticorps

Épitope: AA 39-406

Fonction: Anti-ANGPTL4 Antibody

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human ANGPTL4 shares 75.6%,76.6% amino acid (aa) sequence identity with mouse,rat ANGPTL4,respectively.

Attributs du produit: Anti-ANGPTL4 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ANGPTL4 recombinant protein (Position: D39-S406). Human ANGPTL4 shares 75.6% and 76.6% amino acid (aa) sequence identity with mouse and rat ANGPTL4, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ANGPTL4

Antigène: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Autre désignation: ANGPTL4

Sujet:

Background: Angiopoietin-like 4 is a protein that in humans is encoded by the ANGPTL4 gene.[5][6][7] Alternatively spliced transcript variants encoded with different isoforms have been described. This gene was previously referred to as ANGPTL2, HFARP, PGAR, or FIAF but has been renamed ANGPTL4. This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.

Gene Full Name: angiopoietin like 4

Poids moléculaire: 40-50 kDa

ID gène: 51129

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha