Anillin anticorps (C-Term) (Fluoro594)

N° du produit ABIN7968755

L’anticorps anti-Anillin Polyclonal Lapin est utilisé pour la détection de Anillin dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour Anillin anticorps (C-Term) (Fluoro594) (ABIN7968755)

Antigène: Anillin (ANLN) (Anillin, Actin Binding Protein (ANLN))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Anillin est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-Anillin anticorps (Fluoro594)

Épitope: C-Term

Fonction: Anti-Anillin/ANLN Antibody Fluoro594 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Anillin/ANLN, which shares 96.4% amino acid (aa) sequence identity with both mouse and rat Anillin/ANLN.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Anillin

Antigène: Anillin (ANLN) (Anillin, Actin Binding Protein (ANLN))

Autre désignation: ANLN

Sujet:

Background: Anillin is a conserved protein implicated in cytoskeletal dynamics during cellularization and cytokinesis. This gene is mapped to 7p14.2. The ANLN gene in humans and the scraps gene in Drosophila encode Anillin. The human anillin cDNA, located on Chr7, encodes a 1,125-amino acid protein with a predicted molecular mass of 124 kD and a pI of 8.1. The mouse anillin gene is located on Chr9. This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: anillin, actin binding protein

ID gène: 54443

UniProt: Q9NQW6