Aquaporin 4 anticorps (C-Term) (APC)

N° du produit ABIN7969737

Cet anticorps Lapin Polyclonal détecte spécifiquement Aquaporin 4 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Aquaporin 4 anticorps (C-Term) (APC) (ABIN7969737)

Antigène: Aquaporin 4 (AQP4)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aquaporin 4 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-Aquaporin 4 anticorps (APC)

Épitope: C-Term

Fonction: Anti-Aquaporin 4/AQP4 Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related rat,mouse sequences by two amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Aquaporin 4, different from the related rat and mouse sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Aquaporin 4

Antigène: Aquaporin 4 (AQP4)

Autre désignation: AQP4

Sujet:

Background: AQP4 (Aquaporin 4), also known as MERCURIAL-INSENSITIVE WATER CHANNEL, MIWC, is protein which in humans is encoded by the AQP4 gene. The aquaporins are a family of water-selective membrane channels found in animals, plants, and microorganisms. AQP4 is the predominant water channel in the brain and has an important role in brain water homeostasis. By fluorescence in situ hybridization, Lu et al. (1996) determined that the AQP4 gene maps to 18q11.2-q12.1. By interspecific backcross analysis, Turtzo et al. (1997) mapped the mouse Aqp4 gene to the proximal region of chromosome 18. Analyzing the expression of AQP4 in mammalian skeletal muscle, Frigeri et al. (1998) found that, in immunohistochemical experiments, affinity-purified AQP4 antibodies stained selectively the sarcolemma of fast-twitch fibers. Immunocytochemistry revealed strong AQP4 water channel expression in Muller cells in mouse retina and in fibrous astrocytes in optic nerve.

Gene Full Name: aquaporin 4

Sequence Similarities: Belongs to the MIP/aquaporin (TC 1.A.8) family.

ID gène: 361

UniProt: P55087

Pathways: Sensory Perception of Sound