ALOX12 anticorps (C-Term)
Aperçu rapide pour ALOX12 anticorps (C-Term) (ABIN7969817)
Antigène
Voir toutes ALOX12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- C-Term
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Fonction
- Anti-12 Lipoxygenase/ALOX12 Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- different from the related rat sequence by four amino acids,and from the related mouse sequence by five amino acids.
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Attributs du produit
- Anti-12 Lipoxygenase/ALOX12 Antibody-1. Tested in WB applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human ALOX12, different from the related rat sequence by four amino acids, and from the related mouse sequence by five amino acids.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL, Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide, Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))
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Autre désignation
- ALOX12
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Sujet
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Background: ALOX12, Arachidonate 12-lipoxygenase, is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the ALOX12 gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of DNAArachidonate 12-lipoxygenase introduces a molecular oxygen into the C-12 position of arachidonic acid to produce 12 (S)-hydroperoxy-5,8,10,14-eicosatetraenoic acid. The major pathway of arachidonic acid metabolism in human platelets proceeds via a 12-lipoxygenase enzyme. Expression of the LOG12 gene was detected in human erythroleukemia cells, platelets, and human umbilical vein endothelial cells by reverse transcription-PCR analysis.
Gene Full Name: arachidonate 12-lipoxygenase, 12S type
Sequence Similarities: Belongs to the lipoxygenase family.
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Poids moléculaire
- 75 kDa
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ID gène
- 7314
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UniProt
- P18054
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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