ALOX12 anticorps (AA 186-628) (Fluoro594)

N° du produit ABIN7969833

Cet anticorps Lapin Polyclonal détecte spécifiquement ALOX12 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ALOX12 anticorps (AA 186-628) (Fluoro594) (ABIN7969833)

Antigène: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOX12 est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-ALOX12 anticorps (Fluoro594)

Épitope: AA 186-628

Fonction: Anti-ALOX12 Antibody Fluoro594 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human ALOX12 shares 87.3%,86% amino acid (aa) sequence identity with mouse,rat ALOX12,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ALOX12 recombinant protein (Position: A186-R628). Human ALOX12 shares 87.3% and 86% amino acid (aa) sequence identity with mouse and rat ALOX12, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur ALOX12

Antigène: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Autre désignation: ALOX12

Sujet:

Background: ALOX12, Arachidonate 12-lipoxygenase, is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the ALOX12 gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of DNA Arachidonate 12-lipoxygenase introduces a molecular oxygen into the C-12 position of arachidonic acid to produce 12(S)-hydroperoxy-5,8,10,14-eicosatetraenoic acid. The major pathway of arachidonic acid metabolism in human platelets proceeds via a 12-lipoxygenase enzyme. Expression of the LOG12 gene was detected in human erythroleukemia cells, platelets, and human umbilical vein endothelial cells by reverse transcription-PCR analysis.

Gene Full Name: arachidonate 12-lipoxygenase, 12S type

ID gène: 239

UniProt: P18054

Pathways: Positive Regulation of Endopeptidase Activity