ALOX12 anticorps (AA 186-628)
Aperçu rapide pour ALOX12 anticorps (AA 186-628) (ABIN7969839)
Antigène
Voir toutes ALOX12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 186-628
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Fonction
- Anti-ALOX12 Antibody
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Réactivité croisée (Details)
- No cross reactivity with other proteins.
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Homologie
- Human ALOX12 shares 87.3%,86% amino acid (aa) sequence identity with mouse,rat ALOX12,respectively.
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Attributs du produit
- Anti-ALOX12 Antibody. Tested in ELISA, ICC/IF, WB applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human ALOX12 recombinant protein (Position: A186-R628). Human ALOX12 shares 87.3% and 86% amino acid (aa) sequence identity with mouse and rat ALOX12, respectively.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))
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Autre désignation
- ALOX12
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Sujet
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Background: ALOX12, Arachidonate 12-lipoxygenase, is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the ALOX12 gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of DNA Arachidonate 12-lipoxygenase introduces a molecular oxygen into the C-12 position of arachidonic acid to produce 12(S)-hydroperoxy-5,8,10,14-eicosatetraenoic acid. The major pathway of arachidonic acid metabolism in human platelets proceeds via a 12-lipoxygenase enzyme. Expression of the LOG12 gene was detected in human erythroleukemia cells, platelets, and human umbilical vein endothelial cells by reverse transcription-PCR analysis.
Gene Full Name: arachidonate 12-lipoxygenase, 12S type
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Poids moléculaire
- 75 kDa
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ID gène
- 239
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UniProt
- P18054
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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