ALOX15 anticorps (AA 2-337) (HRP)

N° du produit ABIN7969846

L’anticorps anti-ALOX15 Polyclonal Lapin est utilisé pour la détection de ALOX15 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour ALOX15 anticorps (AA 2-337) (HRP) (ABIN7969846)

Antigène: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOX15 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-ALOX15 anticorps (HRP)

Épitope: AA 2-337

Fonction: Anti-15 Lipoxygenase 1/ALOX15 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human ALOX15 shares 72%,73% amino acid (aa) sequences identity with mouse,rat ALOX15,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ALOX15 recombinant protein (Position: G2-P337). Human ALOX15 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat ALOX15, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ALOX15

Antigène: ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

Autre désignation: ALOX15

Sujet:

Background: Arachidonate 15-lipoxygenase, also known as 15 LOX or LOG15, is an enzyme that in humans is encoded by the ALOX15 gene. This gene is mapped to 17p13.2. It is found that ALOX15 is a mutator gene. ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and cancer development/metastasis. Loss of the TP53 gene, or gain-of-function activities resulting from the expression of its mutant forms regulates ALOX15 promoter activity in human and in mouse, albeit in ionally opposite manners.

Gene Full Name: arachidonate 15-lipoxygenase

Sequence Similarities: Belongs to the lipoxygenase family.

ID gène: 246

UniProt: P16050

Pathways: Regulation of Actin Filament Polymerization