Liver Arginase anticorps (AA 25-183) (Fluoro488)

N° du produit ABIN7969919

Cet anticorps anti-Liver Arginase Monoclonal Souris conjugué à Fluoro488 (Clone 2B12) (ABIN7969919) détecte spécifiquement Liver Arginase dans FACS. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris et Singe.

Aperçu rapide pour Liver Arginase anticorps (AA 25-183) (Fluoro488) (ABIN7969919)

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reactivité: Humain, Rat, Souris, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Liver Arginase est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Clone: 2B12

Détail du produit anti-Liver Arginase anticorps (Fluoro488)

Épitope: AA 25-183

Fonction: Anti-liver Arginase/ARG1 Antibody (monoclonal, 2B12) Fluoro488 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human liver Arginase/ARG1 recombinant protein (Position: E25-D183).

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Liver Arginase

Antigène: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Autre désignation: ARG1

Sujet:

Background: ARG1 (arginase, live) is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. The isoform encoded byARG1, referred to as the liver, or A-I, isoform, contributes 98 % of the arginase activity in liver but is also present in red cells. Using a rat liverARG1cDNA clone to probe a human liver cDNA library,Haraguchi et al. (1987)isolated and characterized a cDNA corresponding to theARG1gene.The ARG1 gene is mapped on 6q23.2 and the arginase gene contains 8 exons. By immunologic studies, 90 % of the arginase in red blood cell and liver was precipitated by the antibody, whereas only 50 % of the arginase in kidney, brain, and the gastrointestinal tract reacted with it. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: arginase 1

ID gène: 383

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin