BTLA anticorps (Middle Region) (PE)

N° du produit ABIN7971766

L’anticorps anti-BTLA Polyclonal Lapin est utilisé pour la détection de BTLA dans des échantillons de Humain et Souris. Il a été validé pour FACS.

Aperçu rapide pour BTLA anticorps (Middle Region) (PE) (ABIN7971766)

Antigène: BTLA (B and T Lymphocyte Associated (BTLA))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BTLA est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-BTLA anticorps (PE)

Épitope: Middle Region

Fonction: Anti-CD272/BTLA Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human CD272/BTLA.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur BTLA

Antigène: BTLA (B and T Lymphocyte Associated (BTLA))

Autre désignation: BTLA

Sujet:

Background: B- and T-lymphocyte attenuator is a protein that in humans is encoded by the BTLA gene. BTLA has also been designated as CD272 (cluster of differentiation 272). This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4.

Gene Full Name: B and T lymphocyte associated

ID gène: 151888

UniProt: Q7Z6A9

Pathways: Cancer Immune Checkpoints