BIRC3 anticorps (AA 1-191) (APC)

N° du produit ABIN7972007

Cet anticorps anti-BIRC3 Polyclonal Lapin conjugué à APC (ABIN7972007) détecte spécifiquement BIRC3 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour BIRC3 anticorps (AA 1-191) (APC) (ABIN7972007)

Antigène: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIRC3 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-BIRC3 anticorps (APC)

Épitope: AA 1-191

Fonction: Anti-cIAP2/BIRC3 Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human cIAP2 shares 69.8% amino acid (aa) sequence identity with mouse cIAP2.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human cIAP2 recombinant protein (Position: M1-K191). Human cIAP2 shares 69.8% amino acid (aa) sequence identity with mouse cIAP2.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur BIRC3

Antigène: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Autre désignation: BIRC3

Sujet:

Background: Baculoviral IAP repeat-containing protein 3 (also known as cIAP2) is a protein that in humans is encoded by the BIRC3 gene. cIAP2 is a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.

Gene Full Name: baculoviral IAP repeat containing 3

Sequence Similarities: Belongs to the IAP family.

ID gène: 330

UniProt: Q13489

Pathways: Apoptose, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades