BCAM anticorps (Middle Region) (APC)

N° du produit ABIN7972118

Cet anticorps anti-BCAM Polyclonal Lapin conjugué à APC (ABIN7972118) détecte spécifiquement BCAM dans FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BCAM anticorps (Middle Region) (APC) (ABIN7972118)

Antigène: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCAM est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-BCAM anticorps (APC)

Épitope: Middle Region

Fonction: Anti-CD239/BCAM Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human CD239/BCAM, which shares 84.4% amino acid (aa) sequence identity with both mouse and rat CD239/BCAM.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur BCAM

Antigène: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Autre désignation: BCAM

Sujet:

Background: Basal cell adhesion molecule, also known as Lutheran antigen, is a plasma membraneglycoprotein that in humans is encoded by the BCAM gene. It is mapped to 19q13.32. This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu (a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: basal cell adhesion molecule (Lutheran blood group)

ID gène: 4059

UniProt: P50895