Bestrophin 1 anticorps (AA 9-551) (HRP)

N° du produit ABIN7972603

L’anticorps anti-Bestrophin 1 Polyclonal Lapin est utilisé pour la détection de Bestrophin 1 dans des échantillons de Souris et Rat. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour Bestrophin 1 anticorps (AA 9-551) (HRP) (ABIN7972603)

Antigène: Bestrophin 1 (BEST1)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Bestrophin 1 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Bestrophin 1 anticorps (HRP)

Épitope: AA 9-551

Fonction: Anti-Bestrophin-1/Best1 Antibody HRP Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Mouse Best1 shares 64.3% amino acid (aa) sequence identity with human Best1.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Bestrophin-1/Best1 recombinant protein (Position: V9-E551). Mouse Best1 shares 64.3% amino acid (aa) sequence identity with human Best1.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Bestrophin 1

Antigène: Bestrophin 1 (BEST1)

Autre désignation: Best1

Sujet:

Background: Bestrophin-1 (Best1) is a protein that, in humans, is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

Gene Full Name: bestrophin 1

ID gène: 24115

UniProt: O88870