Butyrylcholinesterase anticorps (AA 263-571)
Aperçu rapide pour Butyrylcholinesterase anticorps (AA 263-571) (ABIN7973509)
Antigène
Voir toutes Butyrylcholinesterase (BCHE) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 263-571
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Fonction
- Anti-Butyrylcholinesterase/BCHE Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- Mouse BCHE shares 78% amino acid (aa) sequence identity with human BCHE.
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Attributs du produit
- Anti-Butyrylcholinesterase/BCHE Antibody. Tested in WB applications. This antibody reacts with Mouse.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived mouse BCHE recombinant protein (Position: K263-E571). Mouse BCHE shares 78% amino acid (aa) sequence identity with human BCHE.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL, Mouse
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- Butyrylcholinesterase (BCHE)
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Autre désignation
- Bche
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Sujet
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Background: Butyrylcholinesterase (BCHE, or BuChE), also known as pseudocholinesterase or plasma cholinesterase, is a non-specific cholinesterase enzyme that hydrolyses many different choline esters. In humans, it is found primarily in the liver and is encoded by the BCHE gene. Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
Gene Full Name: butyrylcholinesterase
Sequence Similarities: Contains 1 CARD domain.
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Poids moléculaire
- 85-90 kDa
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ID gène
- 12038
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UniProt
- Q03311
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Pathways
- Peptide Hormone Metabolism
Antigène
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