Calpain 3 anticorps (AA 42-764) (Fluoro594)
Aperçu rapide pour Calpain 3 anticorps (AA 42-764) (Fluoro594) (ABIN7974362)
Antigène
Voir toutes Calpain 3 (CAPN3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 42-764
-
Fonction
- Anti-Calpain 3/CAPN3 Antibody Fluoro594 Conjugated
-
Homologie
- Human CAPN3 shares 93.5%,94.2% amino acid (aa) sequence identity with mouse,rat CAPN3,respectively.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- E.coli-derived human Calpain 3/CAPN3 recombinant protein (Position: I42-D764). Human CAPN3 shares 93.5% and 94.2% amino acid (aa) sequence identity with mouse and rat CAPN3, respectively.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
Date de péremption
- 12 months
-
-
- Calpain 3 (CAPN3)
-
Autre désignation
- Calpain 3/CAPN3
-
Sujet
-
Background: Calpain-3 is a protein that in humans is encoded by the CAPN3 gene. Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
Gene Full Name: calpain 3
-
ID gène
- 825
-
UniProt
- P20807
-
Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Antigène
-