Calpain 3 anticorps (AA 42-764) (HRP)

N° du produit ABIN7974364

L’anticorps anti-Calpain 3 Polyclonal Lapin est utilisé pour la détection de Calpain 3 dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour Calpain 3 anticorps (AA 42-764) (HRP) (ABIN7974364)

Antigène: Calpain 3 (CAPN3)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calpain 3 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Calpain 3 anticorps (HRP)

Épitope: AA 42-764

Fonction: Anti-Calpain 3/CAPN3 Antibody HRP Conjugated

Homologie: Human CAPN3 shares 93.5%,94.2% amino acid (aa) sequence identity with mouse,rat CAPN3,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Calpain 3/CAPN3 recombinant protein (Position: I42-D764). Human CAPN3 shares 93.5% and 94.2% amino acid (aa) sequence identity with mouse and rat CAPN3, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Calpain 3

Antigène: Calpain 3 (CAPN3)

Autre désignation: Calpain 3/CAPN3

Sujet:

Background: Calpain-3 is a protein that in humans is encoded by the CAPN3 gene. Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.

Gene Full Name: calpain 3

ID gène: 825

UniProt: P20807

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development