Calpain 6 anticorps (AA 1-641) (PE)

N° du produit ABIN7974388

L’anticorps anti-Calpain 6 Polyclonal Lapin est utilisé pour la détection de Calpain 6 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour Calpain 6 anticorps (AA 1-641) (PE) (ABIN7974388)

Antigène: Calpain 6 (CAPN6)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calpain 6 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-Calpain 6 anticorps (PE)

Épitope: AA 1-641

Fonction: Anti-Calpain 6/CAPN6 Antibody PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human Calpain 6,CAPN6 shares 95.2%,95% amino acid (aa) sequence identity with mouse,rat Calpain 6,CAPN6,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Calpain 6/CAPN6 recombinant protein (Position: M1-L641). Human Calpain 6/CAPN6 shares 95.2% and 95% amino acid (aa) sequence identity with mouse and rat Calpain 6/CAPN6, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Calpain 6

Antigène: Calpain 6 (CAPN6)

Autre désignation: CAPN6

Sujet:

Background: Calpain-6 (also known as calpamodulin) is a protein in humans that is encoded by the CAPN6 gene. Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

Gene Full Name: calpain 6

ID gène: 827

UniProt: Q9Y6Q1