Calpastatin anticorps (Middle Region) (PE)

N° du produit ABIN7974399

Cet anticorps Lapin Polyclonal détecte spécifiquement Calpastatin dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Calpastatin anticorps (Middle Region) (PE) (ABIN7974399)

Antigène: Calpastatin (CAST)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calpastatin est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-Calpastatin anticorps (PE)

Épitope: Middle Region

Fonction: Anti-Calpastatin/CAST Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by fifteen amino acids,and from the related rat sequence by eleven amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human Calpastatin, different from the related mouse sequence by fifteen amino acids, and from the related rat sequence by eleven amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Calpastatin

Antigène: Calpastatin (CAST)

Autre désignation: CAST

Sujet:

Background: Calpastatin is a protein that in humans is encoded by the CAST gene. It is mapped to 5q15. The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Full Name: calpastatin

ID gène: 831

UniProt: P20810