CPB2 anticorps (AA 165-387) (HRP)

N° du produit ABIN7974859

L’anticorps anti-CPB2 Polyclonal Lapin est utilisé pour la détection de CPB2 dans des échantillons de Souris. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour CPB2 anticorps (AA 165-387) (HRP) (ABIN7974859)

Antigène: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPB2 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-CPB2 anticorps (HRP)

Épitope: AA 165-387

Fonction: Anti-Carboxypeptidase B2/CPB2 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: coli-derived mouse CPB2 recombinant protein (Position: K165-D387). Mouse CPB2 shares 86.1%,96.9% amino acid (aa) sequence identity with human,rat CPB2,respectively.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse CPB2 recombinant protein (Position: K165-D387). Mouse CPB2 shares 86.1% and 96.9% amino acid (aa) sequence identity with human and rat CPB2, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CPB2

Antigène: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Autre désignation: Cpb2

Sujet:

Background: Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.

Gene Full Name: carboxypeptidase B2

ID gène: 56373

UniProt: Q9JHH6

Pathways: Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis