CPB2 anticorps (AA 165-387)
Aperçu rapide pour CPB2 anticorps (AA 165-387) (ABIN7974863)
Antigène
Voir toutes CPB2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 165-387
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Fonction
- Anti-Carboxypeptidase B2/CPB2 Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- coli-derived mouse CPB2 recombinant protein (Position: K165-D387). Mouse CPB2 shares 86.1%,96.9% amino acid (aa) sequence identity with human,rat CPB2,respectively.
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Attributs du produit
- Anti-Carboxypeptidase B2/CPB2 Antibody. Tested in WB applications. This antibody reacts with Mouse.
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Purification
- Immunogen affinity purified.
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Immunogène
- E. coli-derived mouse CPB2 recombinant protein (Position: K165-D387). Mouse CPB2 shares 86.1% and 96.9% amino acid (aa) sequence identity with human and rat CPB2, respectively.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL, Mouse
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
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Autre désignation
- Cpb2
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Sujet
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Background: Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.
Gene Full Name: carboxypeptidase B2
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Poids moléculaire
- 48 kDa
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ID gène
- 56373
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UniProt
- Q9JHH6
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Pathways
- Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
Antigène
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