CTSC anticorps (AA 22-463) (APC)

N° du produit ABIN7975829

Cet anticorps anti-CTSC Polyclonal Lapin conjugué à APC (ABIN7975829) détecte spécifiquement CTSC dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CTSC anticorps (AA 22-463) (APC) (ABIN7975829)

Antigène: CTSC (Cathepsin C (CTSC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTSC est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-CTSC anticorps (APC)

Épitope: AA 22-463

Fonction: Anti-CTSC Antibody APC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CTSC recombinant protein (Position: V22-L463).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CTSC

Antigène: CTSC (Cathepsin C (CTSC))

Autre désignation: CTSC

Sujet:

Background: Cathepsin C (CTSC) also known as dipeptidyl peptidase I (DPP-I) is a lysosomal exo-cysteine protease belonging to the peptidase C1 protein family, a subgroup of the cysteine cathepsins. In humans, it is encoded by the CTSC gene. This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.

Gene Full Name: cathepsin C

ID gène: 1075

UniProt: P53634