CNOT7 anticorps (AA 3-285) (APC)

N° du produit ABIN7976148

Cet anticorps Lapin Polyclonal détecte spécifiquement CNOT7 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CNOT7 anticorps (AA 3-285) (APC) (ABIN7976148)

Antigène: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNOT7 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-CNOT7 anticorps (APC)

Épitope: AA 3-285

Fonction: Anti-CNOT7 Antibody APC Conjugated

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CNOT7 recombinant protein (Position: A3-S285).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CNOT7

Antigène: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Autre désignation: CNOT7

Sujet:

Background: CCR4-NOT transcription complex subunit 7 is a protein that in humans is encoded by the CNOT7 gene. The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.

Gene Full Name: CCR4-NOT transcription complex subunit 7

ID gène: 29883

UniProt: Q9UIV1

Pathways: Ribonucleoprotein Complex Subunit Organization