CD16 anticorps (AA 31-215) (Fluoro550)

N° du produit ABIN7976232

Cet anticorps Lapin Polyclonal détecte spécifiquement CD16 dans FACS. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour CD16 anticorps (AA 31-215) (Fluoro550) (ABIN7976232)

Antigène: CD16

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD16 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-CD16 anticorps (Fluoro550)

Épitope: AA 31-215

Fonction: Anti-CD16/Fcgr3 Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse CD16/Fcgr3 recombinant protein (Position: A31-T215).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CD16

Antigène: CD16

Autre désignation: Fcgr3

Sujet:

Background: Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.

Gene Full Name: Fc receptor, IgG, low affinity III

ID gène: 14131

UniProt: P08508

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process