CD1a anticorps (Middle Region) (Fluoro647)

N° du produit ABIN7976359

L’anticorps anti-CD1a Polyclonal Lapin est utilisé pour la détection de CD1a dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour CD1a anticorps (Middle Region) (Fluoro647) (ABIN7976359)

Antigène: CD1a

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD1a est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-CD1a anticorps (Fluoro647)

Épitope: Middle Region

Fonction: Anti-CD1a Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human CD1a.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CD1a

Antigène: CD1a

Autre désignation: CD1A

Sujet:

Background: CD1A (Thymocyte antigen CD1A) also known as CD1, is a human protein encoded by the CD1A gene. CD1A is 1 of 5 distinct CD1 genes that are variably conserved in different mammalian species. This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin.The CD1A gene is mapped on 1q23.1. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. CD1A is concentrated in the early or recycling endosome. Moody et al. (2004) reported that CD1A presents to T cells a family of previously unknown lipopeptides from Mycobacterium tuberculosis, named didehydroxymycobactins because of their structural relation to mycobactin siderophores. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Apolipoprotein E (107741) binds lipid antigens and delivers them by receptor-mediated uptake into endosomal compartments containing CD1 in antigen-presenting cells.

Gene Full Name: CD1a molecule

Sequence Similarities: Contains 9 SRCR domains.

ID gène: 909

UniProt: P06126

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process