CD226 anticorps (AA 19-254)

N° du produit ABIN7976558

Cet anticorps anti-CD226 Polyclonal Lapin (ABIN7976558) détecte spécifiquement CD226 dans WB, FACS et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CD226 anticorps (AA 19-254) (ABIN7976558)

Antigène: CD226

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD226 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Classe de qualité: Carrier-free

Détail du produit anti-CD226 anticorps

Épitope: AA 19-254

Fonction: Anti-CD226 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-CD226 Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CD226 recombinant protein (Position: E19-A254).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CD226

Antigène: CD226

Autre désignation: CD226

Sujet:

Background: DNAM 1, also known as CD226, is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.

Gene Full Name: CD226 Molecule

Poids moléculaire: 70 kDa

ID gène: 10666

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints