CD276 anticorps (AA 29-458) (Fluoro647)

N° du produit ABIN7976645

Cet anticorps anti-CD276 Polyclonal Lapin conjugué à Fluoro647 (ABIN7976645) détecte spécifiquement CD276 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD276 anticorps (AA 29-458) (Fluoro647) (ABIN7976645)

Antigène: CD276

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD276 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-CD276 anticorps (Fluoro647)

Épitope: AA 29-458

Fonction: Anti-CD276 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CD276 recombinant protein (Position: L29-Q458).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CD276

Antigène: CD276

Autre désignation: CD276

Sujet:

Background: Cluster of Differentiation 276 (CD276) or B7 Homolog 3 (B7-H3) is a human protein encoded by the CD276 gene. The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: CD276 Molecule

ID gène: 80381

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints