CD46 anticorps (N-Term)

N° du produit ABIN7977031

L’anticorps anti-CD46 Polyclonal Lapin est utilisé pour la détection de CD46 dans des échantillons de Souris. Il a été validé pour WB.

Aperçu rapide pour CD46 anticorps (N-Term) (ABIN7977031)

Antigène: CD46

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD46 est non-conjugé

Application: Western Blotting (WB)

Classe de qualité: Carrier-free

Détail du produit anti-CD46 anticorps

Épitope: N-Term

Fonction: Anti-CD46 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: different from the related human sequence by twelve amino acids,and from the related rat sequence by nine amino acids.

Attributs du produit: Anti-CD46 Antibody. Tested in WB applications. This antibody reacts with Mouse.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of mouse CD46, different from the related human sequence by twelve amino acids, and from the related rat sequence by nine amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Mouse

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CD46

Antigène: CD46

Autre désignation: Cd46

Sujet:

Background: CD46 complement regulatory protein,?also known as?CD46 (cluster of differentiation?46) and?Membrane Cofactor Protein,?is a?protein?which in humans is encoded by the?CD46 gene. The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. And the encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.?

Gene Full Name: CD46 antigen, complement regulatory protein

Poids moléculaire: 41 kDa, 70 kDa

ID gène: 17221

UniProt: O88174

Pathways: Regulation of Actin Filament Polymerization