CD59a anticorps (AA 24-96) (FITC)

N° du produit ABIN7977202

L’anticorps anti-CD59a Polyclonal Lapin est utilisé pour la détection de CD59a dans des échantillons de Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour CD59a anticorps (AA 24-96) (FITC) (ABIN7977202)

Antigène: CD59a (CD59A)

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD59a est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-CD59a anticorps (FITC)

Épitope: AA 24-96

Fonction: Anti-CD59/Cd59a Antibody FITC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse CD59 recombinant protein (Position: L24-S96).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CD59a

Antigène: CD59a (CD59A)

Autre désignation: Cd59a

Sujet:

Background: CD59 glycoprotein, also known as MAC-inhibitory protein (MAC-IP), membrane inhibitor of reactive lysis (MIRL), or protectin, is a protein that in humans is encoded by the CD59 gene. This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Gene Full Name: CD59a antigen

ID gène: 12509

UniProt: O55186