CDC6 anticorps (C-Term) (Fluoro550)

N° du produit ABIN7977960

Cet anticorps Lapin Polyclonal détecte spécifiquement CDC6 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CDC6 anticorps (C-Term) (Fluoro550) (ABIN7977960)

Antigène: CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC6 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-CDC6 anticorps (Fluoro550)

Épitope: C-Term

Fonction: Anti-Cdc6 Antibody Fluoro550 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Cdc6.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur CDC6

Antigène: CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))

Autre désignation: CDC6

Sujet:

Background: Cell division control ptotein 6 homolog, also called CDC18L or CDC6, is a protein that in humans is encoded by the CDC6 gene. By analysis of somatic cell hybrids and by fluorescence in situ hybridization, this gene is mapped to 17q21.2. The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. This gene is involved in the initiation of DNA replication.

Gene Full Name: cell division cycle 6

Sequence Similarities: Belongs to the CDC6/cdc18 family.

ID gène: 990

UniProt: Q99741

Pathways: DNA Replication, Synthesis of DNA