Ceruloplasmin anticorps (AA 20-259)
Aperçu rapide pour Ceruloplasmin anticorps (AA 20-259) (ABIN7978231)
Antigène
Voir toutes Ceruloplasmin (CP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 20-259
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Fonction
- Anti-Ceruloplasmin/CP Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Homologie
- coli-derived human Ceruloplasmin recombinant protein (Position: K20-M259). Human Ceruloplasmin shares 80.8%,79.6% amino acid (aa) sequence identity with mouse,rat Ceruloplasmin,respectively.
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Attributs du produit
- Anti-Ceruloplasmin/CP Antibody. Tested in Flow Cytometry, WB applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- E. coli-derived human Ceruloplasmin recombinant protein (Position: K20-M259). Human Ceruloplasmin shares 80.8% and 79.6% amino acid (aa) sequence identity with mouse and rat Ceruloplasmin, respectively.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))
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Autre désignation
- CP
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Sujet
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Background: Ceruloplasmin (or caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene. It is mapped to 3q23-q25. The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe (II)transferrin to Fe (III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Gene Full Name: ceruloplasmin
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Poids moléculaire
- 122 kDa
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ID gène
- 1356
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UniProt
- P00450
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Pathways
- Transition Metal Ion Homeostasis
Antigène
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