Ceruloplasmin anticorps (AA 20-258)

N° du produit ABIN7978242

Cet anticorps Lapin Polyclonal détecte spécifiquement Ceruloplasmin dans WB et IHC. Il présente une réactivité avec des échantillons de Rat et Souris.

Aperçu rapide pour Ceruloplasmin anticorps (AA 20-258) (ABIN7978242)

Antigène: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ceruloplasmin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Classe de qualité: Carrier-free

Détail du produit anti-Ceruloplasmin anticorps

Épitope: AA 20-258

Fonction: Anti-Ceruloplasmin/CP Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: coli-derived mouse Ceruloplasmin recombinant protein (Position: R20-M258). Mouse Ceruloplasmin shares 80.8%,91.2% amino acid (aa) sequence identity with human,rat Ceruloplasmin,respectively.

Attributs du produit: Anti-Ceruloplasmin/CP Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse Ceruloplasmin recombinant protein (Position: R20-M258). Mouse Ceruloplasmin shares 80.8% and 91.2% amino acid (aa) sequence identity with human and rat Ceruloplasmin, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Ceruloplasmin

Antigène: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Autre désignation: Cp

Sujet:

Background: Ceruloplasmin  (or caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene. It is mapped to 3q23-q25. The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe (II)transferrin to Fe (III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Gene Full Name: ceruloplasmin

Poids moléculaire: 130 kDa

ID gène: 12870

UniProt: Q61147

Pathways: Transition Metal Ion Homeostasis