IL22 Receptor alpha 1 anticorps (AA 41-150)

N° du produit ABIN748178

L’anticorps Lapin Polyclonal anti-IL22 Receptor alpha 1 a été validé pour WB, ELISA et IHC (p). Il convient pour détecter IL22 Receptor alpha 1 dans des échantillons de Humain et Souris. Il y a 2+ publications disponibles.

Aperçu rapide pour IL22 Receptor alpha 1 anticorps (AA 41-150) (ABIN748178)

Antigène: IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL22 Receptor alpha 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-IL22 Receptor alpha 1 anticorps

Épitope: AA 41-150

Réactivité croisée: Humain, Souris

Homologie: Rat,Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IL-22R

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-IL22 Receptor alpha 1 (ABIN748178)

Zhang, Kolonin: "Cytokine signaling regulating adipose stromal cell trafficking." dans: Adipocyte, Vol. 5, Issue 4, pp. 369-374, (2016) (PubMed).

Guo, Wu, Cen, Li, Kong, Zhou: "IL-22-producing Th22 cells play a protective role in CVB3-induced chronic myocarditis and dilated cardiomyopathy by inhibiting myocardial fibrosis." dans: Virology journal, Vol. 11, Issue 1, pp. 2511, (2014) (PubMed).

Détails sur IL22 Receptor alpha 1

Antigène: IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))

Autre désignation: IL22RA1

Sujet:

Synonyms: IL22R, CRF2-9, IL22R1, Interleukin-22 receptor subunit alpha-1, IL-22 receptor subunit alpha-1, IL-22R-alpha-1, IL-22RA1, Cytokine receptor class-II member 9, Cytokine receptor family 2 member 9, ZcytoR11, IL22RA1

Background: Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.

ID gène: 58985

UniProt: Q8N6P7